PASCAL - Pattern Analysis, Statistical Modelling and Computational Learning

Hallucinations in Charles Bonnet Syndrome Induced by Homeostasis: a Deep Boltzmann Machine Model
David Reichert, Peggy Series and Amos Storkey
Advances in Neural Information Processing Systems Volume 23, pp. 2020-2028, 2011.


The Charles Bonnet Syndrome (CBS) is characterized by complex vivid visual hallucinations in people with, primarily, eye diseases and no other neurological pathology. We present a Deep Boltzmann Machine model of CBS, exploring two core hypotheses: First, that the visual cortex learns a generative or predictive model of sensory input, thus explaining its capability to generate internal imagery. And second, that homeostatic mechanisms stabilize neuronal activity levels, leading to hallucinations being formed when input is lacking. We reproduce a variety of qualitative findings in CBS. We also introduce a modification to the DBM that allows us to model a possible role of acetylcholine in CBS as mediating the balance of feed-forward and feed-back processing. Our model might provide new insights into CBS and also demonstrates that generative frameworks are promising as hypothetical models of cortical learning and perception.

EPrint Type:Article
Project Keyword:Project Keyword UNSPECIFIED
Subjects:Computational, Information-Theoretic Learning with Statistics
Machine Vision
Learning/Statistics & Optimisation
Theory & Algorithms
ID Code:7529
Deposited By:Amos Storkey
Deposited On:17 March 2011