Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients
Salla Ruosaari, Tuija Hienonen-Kempas, Anne Puustinen, Virinder K. Sarhadi, Jaakko Hollmen, Sakari Knuutila, Juha Saharinen, Harriet Wikman and Sisko Anttila
BMC Medical Genomics 2008.

Abstract

Studies on asbestos-induced tumourigenesis have indicated the role of, e.g., reactive oxygen/nitrogen species, mitochondria, as well as NF-кB and MAPK signalling pathways. The exact molecular mechanisms contributing to asbestos-mediated carcinogenesis are, however, still to be characterized

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