Constrained Hidden Markov Models for Population-based Haplotyping (Extended Abstract)
Niels Landwehr, Taneli Mielikäinen, Lauri Eronen, Hannu Toivonen and Heikki Mannila
In: PMSB 2006, 17-18 Jun 2006, Tuusula, Finland.

Abstract

We propose a simple haplotype reconstruction method that is based on iterative refinement and regularization of constrained Hidden Markov Models. We show that it gives results comparable to the state-of-the-art methods in haplotyping.

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